BioDrone® is an innovative drug delivery platform technology that relies on tiny vesicles obtained from diverse cell sources, called cell-derived vesicles (CDVs), by using the proprietary extrusion method.
Recently, extracellular vesicles (EVs), especially exosomes, have emerged as a novel therapeutic with their roles in intercellular communications. However, the fact that they only naturally occur in minuscule quantities and the difficulties involved in large-scale production have prevented rapid progress in the commercialization of EVs. BioDrone® platform technology was developed to overcome these critical limitations in EV therapeutics.
CDV presents excellent potential as a biosafe, non-viral drug delivery vehicle. Encapsulation of chemical drugs or biomolecular payloads (RNA/DNA/protein), inside the lumen or lipid membrane of CDVs, allows the delivery of drugs into their cellular targets with greater efficiency. On the other hand, surface modification with various tissue-specific moieties will confer a precise targeting capability to this novel carrier.
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